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A selective prostaglandin E2 receptor subtype 2 (EP2) antagonist increases the macrophage-mediated clearance of amyloid-beta plaques.
Fox, Brian M; Beck, Hilary P; Roveto, Philip M; Kayser, Frank; Cheng, Qingwen; Dou, Hannah; Williamson, Toni; Treanor, James; Liu, Hantao; Jin, Lixia; Xu, Guifen; Ma, Ji; Wang, Songli; Olson, Steven H.
Afiliação
  • Fox BM; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Beck HP; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Roveto PM; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Kayser F; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Cheng Q; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Dou H; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Williamson T; ‡Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Treanor J; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Liu H; ‡Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Jin L; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Xu G; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Ma J; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Wang S; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
  • Olson SH; †Amgen South San Francisco, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States.
J Med Chem ; 58(13): 5256-73, 2015 Jul 09.
Article em En | MEDLINE | ID: mdl-26061158
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazepinas / Fagocitose / Piridonas / Bioensaio / Encéfalo / Placa Amiloide / Receptores de Prostaglandina E Subtipo EP2 / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazepinas / Fagocitose / Piridonas / Bioensaio / Encéfalo / Placa Amiloide / Receptores de Prostaglandina E Subtipo EP2 / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article