[Genetic diversity of X-linked STR-markers in Siberian populations].
Mol Biol (Mosk)
; 49(2): 305-12, 2015.
Article
em Ru
| MEDLINE
| ID: mdl-26065258
ABSTRACT
X-chromosome markers are informative tool for studying of the genetic diversity in human populations and become useful for DNA identification when certain complex kinship cases need to be unraveled. In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789). Average level of expected heterozygosity (He) in populations under study was 0.73. Total level of genetic differentiation for 10 studied populations was relatively low (Fst = 0.031 comparing to autosomal and Y-chromosomal markers. Allele frequencies and parameters of forensic interest for panel of X-STRs were calculated. The overall values of PDf and PDm are 0.9999999997, 0.999998 respectively. The overall level of genetic differentiation for 10 population (Fst) is 0.03186.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Marcadores Genéticos
/
Cromossomos Humanos X
/
Cromossomos Humanos Y
Limite:
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
Ru
Ano de publicação:
2015
Tipo de documento:
Article