Can we use peripheral tissue biopsies to diagnose Parkinson's disease? A review of the literature.

Schneider, S A; Boettner, M; Alexoudi, A; Zorenkov, D; Deuschl, G; Wedel, T

Schneider, S A; Boettner, M; Alexoudi, A; Zorenkov, D; Deuschl, G; Wedel, T.

Afiliação

Schneider SA; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Boettner M; Institute of Anatomy, Christian Albrecht's University of Kiel, Kiel, Germany.
Alexoudi A; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Zorenkov D; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Deuschl G; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Wedel T; Institute of Anatomy, Christian Albrecht's University of Kiel, Kiel, Germany.

Eur J Neurol ; 23(2): 247-61, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26100920

Assuntos

Biomarcadores/metabolismo; Trato Gastrointestinal/metabolismo; Doença de Parkinson/diagnóstico; Glândulas Salivares/metabolismo; alfa-Sinucleína/análise; alfa-Sinucleína/metabolismo; Trato Gastrointestinal/patologia; Humanos; Doença de Parkinson/metabolismo; Doença de Parkinson/patologia; Glândulas Salivares/patologia

Palavras-chave

Parkinson's disease; alpha synuclein; biopsy; gastrointestinal tract; immunohistochemistry; olfactory mucosa; phosphorylated alpha synuclein; pre-motor stage; salivary glands; skin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Glândulas Salivares / Biomarcadores / Trato Gastrointestinal / Alfa-Sinucleína Tipo de estudo: Diagnostic_studies / Guideline / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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