The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer's Disease.

Qian, Meng; Shen, Xiaoqiang; Wang, Huanhuan

Qian, Meng; Shen, Xiaoqiang; Wang, Huanhuan.

Afiliação

Qian M; Key Lab of Inflammation and Immunoregulation, School of Medicine, Hangzhou Normal University, Xuelin Street 16, Hangzhou, 310036, China.
Shen X; Key Lab of Inflammation and Immunoregulation, School of Medicine, Hangzhou Normal University, Xuelin Street 16, Hangzhou, 310036, China.
Wang H; Key Lab of Inflammation and Immunoregulation, School of Medicine, Hangzhou Normal University, Xuelin Street 16, Hangzhou, 310036, China. huanval@hznu.edu.cn.

Cell Mol Neurobiol ; 36(4): 471-82, 2016 May.

Article em En | MEDLINE | ID: mdl-26119306

Assuntos

Proteína ADAM17/metabolismo; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/metabolismo; Microglia/patologia; Proteólise; Proteína ADAM17/química; Animais; Humanos; Inflamação/patologia

Palavras-chave

ADAM17; Alzheimer's disease; Neuroinflammation; α-Secretase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Microglia / Doença de Alzheimer / Proteólise / Proteína ADAM17 Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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