The potential of random forest and neural networks for biomass and recombinant protein modeling in Escherichia coli fed-batch fermentations.

Melcher, Michael; Scharl, Theresa; Spangl, Bernhard; Luchner, Markus; Cserjan, Monika; Bayer, Karl; Leisch, Friedrich; Striedner, Gerald

Melcher, Michael; Scharl, Theresa; Spangl, Bernhard; Luchner, Markus; Cserjan, Monika; Bayer, Karl; Leisch, Friedrich; Striedner, Gerald.

Afiliação

Melcher M; Austrian Centre of Industrial Biotechnology, Graz, Austria. m.melcher@boku.ac.at.
Scharl T; Institute of Applied Statistics and Computing, University of Natural Resources and Life Sciences, Vienna, Austria. m.melcher@boku.ac.at.
Spangl B; Austrian Centre of Industrial Biotechnology, Graz, Austria.
Luchner M; Austrian Centre of Industrial Biotechnology, Graz, Austria.
Cserjan M; Institute of Applied Statistics and Computing, University of Natural Resources and Life Sciences, Vienna, Austria.
Bayer K; Austrian Centre of Industrial Biotechnology, Graz, Austria.
Leisch F; Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Striedner G; Austrian Centre of Industrial Biotechnology, Graz, Austria.

Biotechnol J ; 10(11): 1770-82, 2015 Sep.

Article em En | MEDLINE | ID: mdl-26121295

Assuntos

Biomassa; Escherichia coli/metabolismo; Modelos Estatísticos; Redes Neurais de Computação; Engenharia de Proteínas/métodos; Proteínas Recombinantes/metabolismo; Reatores Biológicos; Árvores de Decisões; Escherichia coli/genética; Fermentação

Palavras-chave

Artificial neural networks; Process analytical technology; Quality by design; Random forest; Recombinant protein production

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Engenharia de Proteínas / Modelos Estatísticos / Redes Neurais de Computação / Biomassa / Escherichia coli Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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