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Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.
Chen, Guo-Qing; Tang, Cheng-Fang; Shi, Xiao-Ke; Lin, Cheng-Yuan; Fatima, Sarwat; Pan, Xiao-Hua; Yang, Da-Jian; Zhang, Ge; Lu, Ai-Ping; Lin, Shu-Hai; Bian, Zhao-Xiang.
Afiliação
  • Chen GQ; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Tang CF; Chongqing Academy of Chinese Materia Medica, Chongqing, China.
  • Shi XK; Department of Chemistry and State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong SAR, China.
  • Lin CY; Instrument and Testing Center, Sun Yat-Sen University, Guangzhou, China.
  • Fatima S; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Pan XH; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Yang DJ; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang G; Shen Zhen People's Hospital, Shenzhen, China.
  • Lu AP; Chongqing Academy of Chinese Materia Medica, Chongqing, China.
  • Lin SH; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Bian ZX; Laboratory of Brain and Gut Research, Center for Clinical Research on Chinese Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Oncotarget ; 6(27): 24148-62, 2015 Sep 15.
Article em En | MEDLINE | ID: mdl-26160839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Neoplasias Colorretais / Complexos Multiproteicos / Proteínas Proto-Oncogênicas c-akt / Quinazolinonas / Serina-Treonina Quinases TOR / Glucose Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Neoplasias Colorretais / Complexos Multiproteicos / Proteínas Proto-Oncogênicas c-akt / Quinazolinonas / Serina-Treonina Quinases TOR / Glucose Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article