Effects of selective serotonin reuptake inhibitors on three sex steroids in two versions of the aromatase enzyme inhibition assay and in the H295R cell assay.

Jacobsen, Naja Wessel; Hansen, Cecilie Hurup; Nellemann, Christine; Styrishave, Bjarne; Halling-Sørensen, Bent

Jacobsen, Naja Wessel; Hansen, Cecilie Hurup; Nellemann, Christine; Styrishave, Bjarne; Halling-Sørensen, Bent.

Afiliação

Jacobsen NW; Toxicology Laboratory, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
Hansen CH; Toxicology Laboratory, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
Nellemann C; Division of Toxicology and Risk Assessment, National Food Institute, Technical University of Denmark, Mørkhøj Bygade 19, 2860 Søborg, Denmark.
Styrishave B; Toxicology Laboratory, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
Halling-Sørensen B; Toxicology Laboratory, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark. Electronic address: Bent.halling@sund.ku.dk.

Toxicol In Vitro ; 29(7): 1729-35, 2015 Oct.

Article em En | MEDLINE | ID: mdl-26162595

Assuntos

Inibidores da Aromatase/farmacologia; Estradiol/metabolismo; Progesterona/metabolismo; Inibidores Seletivos de Recaptação de Serotonina/farmacologia; Testosterona/metabolismo; Aromatase/metabolismo; Linhagem Celular Tumoral; Citalopram/farmacologia; Fluoxetina/farmacologia; Fluvoxamina/farmacologia; Humanos; Paroxetina/farmacologia; Sertralina/farmacologia

Palavras-chave

17ß-estradiol; Citalopram; Endocrine disruption; Fluoxetine; Fluvoxamine; Paroxetine; Progesterone; SSRI; Sertraline; Steroidogenesis; Testosterone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Progesterona / Testosterona / Inibidores Seletivos de Recaptação de Serotonina / Inibidores da Aromatase / Estradiol Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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