Twenty-four-hour intraocular pressure monitoring in normotensive patients undergoing chronic hemodialysis.
Eur J Ophthalmol
; 26(1): 24-9, 2016.
Article
em En
| MEDLINE
| ID: mdl-26165324
ABSTRACT
PURPOSE:
To investigate 24-hour intraocular pressure (IOP) changes caused by hemodialysis (HD).METHODS:
A prospective, observational, comparative 24-hour trial was performed on consecutive subjects with normal IOP undergoing maintenance HD 3 days a week between 1300 and 1700 hours in an academic setting. Following a comprehensive ocular assessment, those with conditions that may influence IOP were excluded and one eye was randomly selected. Twenty-four-hour IOP monitoring was performed on HD day 1 and then on a day without HD. The IOP was measured at 1000, 1300, 1500, 1700, 2200, 0200, and 0600 employing Goldmann and Perkins tonometry on habitual position. During the course of 1 year, 18 patients completed the study.RESULTS:
Monitoring of IOP on HD day showed a significantly higher mean 24-hour IOP (15.4 ± 2.7 vs 14.1 ± 2.2 mm Hg; p = 0.025), higher mean peak 24-hour IOP (18.5 ± 3.5 vs 15.8 ± 2.5 mm Hg; p = 0.003), and wider 24-hour IOP fluctuation (6.2 ± 2.3 vs 4.0 ± 1.9 mm Hg; p = 0.001). When individual time points were compared, IOP was significantly higher at 1700 on HD day, reflecting a gradual IOP elevation during HD (p = 0.021). Further, during the HD procedure (1300-1700), the mean IOP was significantly higher on a HD day (16.4 ± 3.0 vs 14.7 ± 2.4 mm Hg; p = 0.004).CONCLUSIONS:
This prospective, before/after trial suggests that HD significantly impacts 24-hour IOP characteristics in normotensive eyes. The long-term significance of these findings requires further elucidation in normotensive patients and, predominantly, in patients with glaucoma undergoing HD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glaucoma de Ângulo Aberto
/
Diálise Renal
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Ritmo Circadiano
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Pressão Intraocular
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Falência Renal Crônica
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
/
Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article