Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene.

Sarachana, Tewarit; Dahiya, Neetu; Simhadri, Vijaya L; Pandey, Gouri Shankar; Saini, Surbhi; Guelcher, Christine; Guerrera, Michael F; Kimchi-Sarfaty, Chava; Sauna, Zuben E; Atreya, Chintamani D

Sarachana, Tewarit; Dahiya, Neetu; Simhadri, Vijaya L; Pandey, Gouri Shankar; Saini, Surbhi; Guelcher, Christine; Guerrera, Michael F; Kimchi-Sarfaty, Chava; Sauna, Zuben E; Atreya, Chintamani D.

Afiliação

Sarachana T; Laboratory of Cellular Hematology, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn Unive
Dahiya N; Laboratory of Cellular Hematology, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.
Simhadri VL; Laboratory of Hemostasis, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.
Pandey GS; Laboratory of Hemostasis, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.
Saini S; Laboratory of Hemostasis, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America; Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, D. C. 2001
Guelcher C; Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, D. C. 20010, United States of America.
Guerrera MF; Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, D. C. 20010, United States of America; School of Medicine and Health Sciences, George Washington University, Washington, D. C. 20037, United States of America.
Kimchi-Sarfaty C; Laboratory of Hemostasis, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.
Sauna ZE; Laboratory of Hemostasis, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.
Atreya CD; Laboratory of Cellular Hematology, Division of Hematology Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States of America.

PLoS One ; 10(7): e0132433, 2015.

Article em En | MEDLINE | ID: mdl-26176629

Assuntos

Fator VIII/metabolismo; Regulação da Expressão Gênica; Hemofilia A/genética; MicroRNAs/genética; MicroRNAs/metabolismo; RNA não Traduzido/sangue; Adolescente; Adulto; Sequência de Bases; Inibidores dos Fatores de Coagulação Sanguínea/sangue; Linhagem Celular Tumoral; Criança; Pré-Escolar; Fator VIII/química; Fator VIII/genética; Perfilação da Expressão Gênica; Hemofilia A/patologia; Humanos; Lactente; Masculino; Análise de Sequência com Séries de Oligonucleotídeos; Alinhamento de Sequência; Regulação para Cima; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator VIII / Regulação da Expressão Gênica / RNA não Traduzido / MicroRNAs / Hemofilia A Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Humans / Infant / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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