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Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils.
Chu, Wenhua; Zhou, Dong; Gaba, Vrinda; Liu, Jialu; Li, Shihong; Peng, Xin; Xu, Jinbin; Dhavale, Dhruva; Bagchi, Devika P; d'Avignon, André; Shakerdge, Naomi B; Bacskai, Brian J; Tu, Zhude; Kotzbauer, Paul T; Mach, Robert H.
Afiliação
  • Chu W; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Zhou D; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Gaba V; ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Liu J; ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Li S; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Peng X; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Xu J; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Dhavale D; ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Bagchi DP; ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • d'Avignon A; §Department of Chemistry, Washington University, St. Louis, Missouri 63130, United States.
  • Shakerdge NB; ∥MassGeneral Institute of Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts 02129, United States.
  • Bacskai BJ; ∥MassGeneral Institute of Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts 02129, United States.
  • Tu Z; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Kotzbauer PT; ‡Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Mach RH; †Department of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
J Med Chem ; 58(15): 6002-17, 2015 Aug 13.
Article em En | MEDLINE | ID: mdl-26177091
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Alfa-Sinucleína / Indóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Alfa-Sinucleína / Indóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article