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Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Liu, Jimmy Z; van Sommeren, Suzanne; Huang, Hailiang; Ng, Siew C; Alberts, Rudi; Takahashi, Atsushi; Ripke, Stephan; Lee, James C; Jostins, Luke; Shah, Tejas; Abedian, Shifteh; Cheon, Jae Hee; Cho, Judy; Dayani, Naser E; Franke, Lude; Fuyuno, Yuta; Hart, Ailsa; Juyal, Ramesh C; Juyal, Garima; Kim, Won Ho; Morris, Andrew P; Poustchi, Hossein; Newman, William G; Midha, Vandana; Orchard, Timothy R; Vahedi, Homayon; Sood, Ajit; Sung, Joseph Y; Malekzadeh, Reza; Westra, Harm-Jan; Yamazaki, Keiko; Yang, Suk-Kyun; Barrett, Jeffrey C; Alizadeh, Behrooz Z; Parkes, Miles; Bk, Thelma; Daly, Mark J; Kubo, Michiaki; Anderson, Carl A; Weersma, Rinse K.
Afiliação
  • Liu JZ; Wellcome Trust Sanger Institute, Hinxton, UK.
  • van Sommeren S; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
  • Huang H; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
  • Ng SC; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Alberts R; Department of Medicine and Therapeutics, Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong.
  • Takahashi A; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
  • Ripke S; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, Riken, Yokohama, Japan.
  • Lee JC; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Jostins L; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, Cambridge, UK.
  • Shah T; Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK.
  • Abedian S; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Cheon JH; Digestive Disease Research Institute, Shariati Hospital, Tehran, Iran.
  • Cho J; Yonsei University College of Medicine, Seoul, Korea.
  • Dayani NE; Icahn School of Medicine, Mount Sinai New York, New York, USA.
  • Franke L; Department of Gastroenterology, Emam Hospital, Tehran, Iran.
  • Fuyuno Y; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
  • Hart A; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, Riken, Yokohama, Japan.
  • Juyal RC; IBD Unit, St Mark's Hospital, Harrow, Middlesex, UK.
  • Juyal G; National Institute of Immunology, Aruna Asaf Ali Road, New Delhi, India.
  • Kim WH; Department of Genetics, University of Delhi South Campus, New Delhi, India.
  • Morris AP; Yonsei University College of Medicine, Seoul, Korea.
  • Poustchi H; Welcome Trust Center for Human Genetics, Oxford U.K. and Department of Biostatistics, University of Liverpool, Liverpool, UK.
  • Newman WG; Digestive Disease Research Institute, Shariati Hospital, Tehran, Iran.
  • Midha V; Manchester Centre for Genomic Medicine, University of Manchester and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
  • Orchard TR; Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, India.
  • Vahedi H; St Mary's Hospital, London, UK.
  • Sood A; Digestive Disease Research Institute, Shariati Hospital, Tehran, Iran.
  • Sung JY; Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, India.
  • Malekzadeh R; Department of Medicine and Therapeutics, Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong.
  • Westra HJ; Digestive Disease Research Institute, Shariati Hospital, Tehran, Iran.
  • Yamazaki K; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
  • Yang SK; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, Riken, Yokohama, Japan.
  • Alizadeh BZ; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Parkes M; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands.
  • Bk T; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, Cambridge, UK.
  • Daly MJ; Department of Genetics, University of Delhi South Campus, New Delhi, India.
  • Kubo M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Anderson CA; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, Riken, Yokohama, Japan.
  • Weersma RK; Wellcome Trust Sanger Institute, Hinxton, UK.
Nat Genet ; 47(9): 979-986, 2015 Sep.
Article em En | MEDLINE | ID: mdl-26192919

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article