Palladium-Catalyzed Direct Dialkenylation of Cage B-H Bonds in o-Carboranes through Cross-Coupling Reactions.
Angew Chem Int Ed Engl
; 54(36): 10623-6, 2015 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-26199199
ABSTRACT
Palladium-catalyzed direct dialkenylation of cage B(4,5)-H bonds in o-carboranes has been achieved with the help of a carboxylic acid directing group, leading to the preparation of a series of 4,5-[trans-(ArCH=CH)]2-ocarboranes in high yields with excellent regioselectivity. The traceless directing group, eliminated during the course of the reaction, is responsible for controlling regioselectivity and dialkenylation. A possible catalytic cycle is proposed, involving a tandem sequence of Pd(II) -initiated cage B-H activation, alkene insertion, ß-H elimination, reductive elimination, and decarboxylation.
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01-internacional
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MEDLINE
Assunto principal:
Paládio
/
Boranos
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Alcenos
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article