The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice That Is Reversed by Tropomyosin Receptor Kinase B Activation.

Warnault, Vincent; Darcq, Emmanuel; Morisot, Nadege; Phamluong, Khanhky; Wilbrecht, Linda; Massa, Stephen M; Longo, Frank M; Ron, Dorit

Warnault, Vincent; Darcq, Emmanuel; Morisot, Nadege; Phamluong, Khanhky; Wilbrecht, Linda; Massa, Stephen M; Longo, Frank M; Ron, Dorit.

Afiliação

Warnault V; Department of Neurology, University of California, San Francisco, San Francisco.
Darcq E; Department of Neurology, University of California, San Francisco, San Francisco.
Morisot N; Department of Neurology, University of California, San Francisco, San Francisco.
Phamluong K; Department of Neurology, University of California, San Francisco, San Francisco.
Wilbrecht L; Department of Psychology, University of California, Berkeley, Berkeley.
Massa SM; Department of Neurology, University of California, San Francisco, San Francisco; Laboratory for Computational Neurochemistry and Drug Discovery and Department of Veterans Affairs Medical Center, University of California, San Francisco, San Francisco.
Longo FM; Department of Neurology and Neurological Sciences (FML), Stanford University School of Medicine, Stanford, California.
Ron D; Department of Neurology, University of California, San Francisco, San Francisco. Electronic address: dorit.ron@ucsf.edu.

Biol Psychiatry ; 79(6): 463-73, 2016 Mar 15.

Article em En | MEDLINE | ID: mdl-26204799

Assuntos

Consumo de Bebidas Alcoólicas/genética; Fator Neurotrófico Derivado do Encéfalo/genética; Comportamento Compulsivo; Proteínas Tirosina Quinases/metabolismo; Receptor trkB/genética; Alcoolismo/genética; Alelos; Animais; Benzamidas/farmacologia; Modelos Animais de Doenças; Metionina/genética; Camundongos; Camundongos Transgênicos; Polimorfismo de Nucleotídeo Único; Valina/genética

Palavras-chave

Addiction; Alcohol; BDNF; Ethanol; Growth factor; Polymorphism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Consumo de Bebidas Alcoólicas / Comportamento Compulsivo / Fator Neurotrófico Derivado do Encéfalo / Receptor trkB Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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