Systematic Analysis of Hollow Fiber Model of Tuberculosis Experiments.

Pasipanodya, Jotam G; Nuermberger, Eric; Romero, Klaus; Hanna, Debra; Gumbo, Tawanda

Pasipanodya, Jotam G; Nuermberger, Eric; Romero, Klaus; Hanna, Debra; Gumbo, Tawanda.

Afiliação

Pasipanodya JG; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas.
Nuermberger E; Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Romero K; Critical Path Institute, Tucson, Arizona.
Hanna D; Critical Path Institute, Tucson, Arizona.
Gumbo T; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas Department of Medicine, University of Cape Town, Observatory, South Africa.

Clin Infect Dis ; 61 Suppl 1: S10-7, 2015 Aug 15.

Article em En | MEDLINE | ID: mdl-26224767

Assuntos

Antituberculosos/farmacologia; Antituberculosos/uso terapêutico; Descoberta de Drogas/métodos; Mycobacterium tuberculosis/efeitos dos fármacos; Tuberculose/tratamento farmacológico; Avaliação Pré-Clínica de Medicamentos; Quimioterapia Combinada; Humanos; Técnicas In Vitro; Modelos Biológicos; Método de Monte Carlo

Palavras-chave

Monte Carlo experiments; PK/PD; hollow fiber system; quantitative drug development tool; tuberculosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Descoberta de Drogas / Mycobacterium tuberculosis / Antituberculosos Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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