Molecular control of stress transmission in the microtubule cytoskeleton.
Biochim Biophys Acta
; 1853(11 Pt B): 3015-24, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26225932
ABSTRACT
In this article, we will summarize recent progress in understanding the mechanical origins of rigidity, strength, resiliency and stress transmission in the MT cytoskeleton using reconstituted networks formed from purified components. We focus on the role of network architecture, crosslinker compliance and dynamics, and molecular determinants of single filament elasticity, while highlighting open questions and future directions for this work.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Mecânico
/
Elasticidade
/
Microtúbulos
Limite:
Animals
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article