Heterotrimeric G protein subunits differentially respond to endoplasmic reticulum stress in Arabidopsis.
Plant Signal Behav
; 10(10): e1061162, 2015.
Article
em En
| MEDLINE
| ID: mdl-26237103
ABSTRACT
Canonical heterotrimeric G proteins in eukaryotes are major components that localize at plasma membrane and transmit extracellular stimuli into the cell. Genome of a seed plant Arabidopsis thaliana encodes at least one Gα (GPA1), one Gß (AGB1), and 3 Gγ (AGG1, AGG2 and AGG3) subunits. The loss-of-function mutations of G protein subunit(s) cause multiple defects in development as well as biotic and abiotic stress responses. However, it remains elusive how these subunits differentially express these defects. Here, we report that Arabidopsis heterotrimeric G protein subunits differentially respond to the endoplasmic reticulum (ER) stress. An isolated homozygous mutant of AGB1, agb1-3, was more sensitive to the tunicamycin-induced ER stress compared to the wild type and the other loss-of-function mutants of G protein subunits. Moreover, ER stress responsive genes were highly expressed in the agb1-3 plant. Our results indicate that AGB1 positively contributes to ER stress tolerance in Arabidopsis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Fisiológico
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Adaptação Fisiológica
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Genes de Plantas
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Arabidopsis
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Subunidades Proteicas
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Proteínas de Arabidopsis
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Subunidades beta da Proteína de Ligação ao GTP
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Estresse do Retículo Endoplasmático
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article