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hERG potassium channel inhibition by ivabradine requires channel gating.
Melgari, Dario; Brack, Kieran E; Zhang, Yihong; El Harchi, Aziza; Mitcheson, John S; Dempsey, Christopher E; Ng, G André; Hancox, Jules C.
Afiliação
  • Melgari D; School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
  • Brack KE; Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.
  • Zhang Y; School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
  • El Harchi A; School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
  • Mitcheson JS; Department of Cell Physiology and Pharmacology, Maurice Shock Medical Sciences Building, University Road, PO Box 138, Leicester LE1 9HN, UK.
  • Dempsey CE; School of Biochemistry, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
  • Ng GA; Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Leicester LE3 9QP, UK.
  • Hancox JC; School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK. Electronic address: jules.hancox@bristol.ac.uk.
J Mol Cell Cardiol ; 87: 126-8, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26275355
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzazepinas / Bloqueadores dos Canais de Potássio / Miócitos Cardíacos / Canais de Potássio Éter-A-Go-Go / Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzazepinas / Bloqueadores dos Canais de Potássio / Miócitos Cardíacos / Canais de Potássio Éter-A-Go-Go / Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article