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Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes.
Julfakyan, Khachatur; Fatieiev, Yevhen; Alsaiari, Shahad; Deng, Lin; Ezzeddine, Alaa; Zhang, Dingyuan; Rotello, Vincent M; Khashab, Niveen M.
Afiliação
  • Julfakyan K; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. khachatur.julfakyan@kaust.edu.sa.
  • Fatieiev Y; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. yevhen.fatieiev@kaust.edu.sa.
  • Alsaiari S; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. shahad.alsaiari@kaust.edu.sa.
  • Deng L; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. lin.deng@kaust.edu.sa.
  • Ezzeddine A; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. alaa.ezzeddine@kaust.edu.sa.
  • Zhang D; Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. zhang-chem@hotmail.com.
  • Rotello VM; Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China. zhang-chem@hotmail.com.
  • Khashab NM; Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA. rotello@chem.umass.edu.
Int J Mol Sci ; 16(8): 18283-92, 2015 Aug 06.
Article em En | MEDLINE | ID: mdl-26287162
ABSTRACT
Polydopamine-coated FeCo nanocubes (PDFCs) were successfully synthesized and tested under microwave irradiation of 2.45 GHz frequency and 0.86 W/cm(2) power. These particles were found to be non-toxic in the absence of irradiation, but gained significant toxicity upon irradiation. Interestingly, no increase in relative heating rate was observed when the PDFCs were irradiated in solution, eliminating nanoparticle (NP)-induced thermal ablation as the source of toxicity. Based on these studies, we propose that microwave-induced redox processes generate the observed toxicity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Nanopartículas de Magnetita / Indóis / Micro-Ondas Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Nanopartículas de Magnetita / Indóis / Micro-Ondas Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article