Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents.
Angew Chem Int Ed Engl
; 54(39): 11526-30, 2015 Sep 21.
Article
em En
| MEDLINE
| ID: mdl-26296530
ABSTRACT
Black phosphorus quantum dots (BPQDs) were synthesized using a liquid exfoliation method that combined probe sonication and bath sonication. With a lateral size of approximately 2.6â
nm and a thickness of about 1.5â
nm, the ultrasmall BPQDs exhibited an excellent NIR photothermal performance with a large extinction coefficient of 14.8 L g(-1)â
cm(-1) at 808â
nm, a photothermal conversion efficiency of 28.4%, as well as good photostability. After PEG conjugation, the BPQDs showed enhanced stability in physiological medium, and there was no observable toxicity to different types of cells. NIR photoexcitation of the BPQDs in the presence of C6 and MCF7 cancer cells led to significant cell death, suggesting that the nanoparticles have large potential as photothermal agents.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fósforo
/
Pontos Quânticos
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article