[Relationship of serum lipids, apolipoproteins and sex hormones with coronary heart disease in postmenopausal women].
Hua Xi Yi Ke Da Xue Xue Bao
; 20(4): 409-12, 1989 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-2630419
ABSTRACT
The study was carried out in 25 postmenopausal women with coronary heart disease (CHD) and 25 matched controls. Age, menopausal time, body mass index, hypertension, smoking and occupation in CHD were not different from those in the control group. Serum lipids, apolipoproteins (apo), sex hormones and gonadotropin hormones were measured. Serum TG and apo AI/apoB100 ratio increased more significantly in CHD than in the control group. Serum apo A II decreased more significantly in CHD than in the control group. Other serum factors in CHD were not significantly different from those in the control group. Matched logistic regression analysis showed that serum TG and apo A I were probable risk factor, serum apo A II was a protected factor of CHD, and all of them were important predictors for CHD in postmenopausal women. Our results suggest that sex hormones seem to have important effects on the occurrence of CHD by esterone (E1) and progesterone (P) interrupting serum lipid and apolipoprotein metabolism. Serum E1 is related with TG, P is positively related with apo B100.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apolipoproteínas
/
Triglicerídeos
/
Menopausa
/
Doença das Coronárias
/
Estradiol
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Zh
Ano de publicação:
1989
Tipo de documento:
Article