Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study.

Kruzliak, Peter; Hare, David L; Zvonicek, Vaclav; Klimas, Jan; Zulli, Anthony

Kruzliak, Peter; Hare, David L; Zvonicek, Vaclav; Klimas, Jan; Zulli, Anthony.

Afiliação

Kruzliak P; International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
Hare DL; Departments of Cardiology and Medicine, University of Melbourne, Austin Health, Melbourne, VIC, Australia.
Zvonicek V; International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
Klimas J; Department of Anesthesiology and Intensive Care Medicine, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
Zulli A; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia.

J Cell Mol Med ; 19(11): 2647-54, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26304628

Assuntos

Anticolesterolemiantes/uso terapêutico; Dieta Aterogênica/efeitos adversos; Fibrose Pulmonar/tratamento farmacológico; Sinvastatina/uso terapêutico; Animais; Proteínas de Choque Térmico HSP70/metabolismo; Proteínas de Choque Térmico HSP90/metabolismo; Pulmão/metabolismo; Pulmão/patologia; Fibrose Pulmonar/etiologia; Fibrose Pulmonar/metabolismo; Fibrose Pulmonar/prevenção & controle; Coelhos; Receptores de Angiotensina/metabolismo

Palavras-chave

Hsp70; Hsp90; cholesterol; diet; fibrosis; methionine; simvastatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Sinvastatina / Dieta Aterogênica / Anticolesterolemiantes Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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