[miRNA as a new marker of diabetes mellitus and pancreatic carcinoma progression]. / miRNA jako nový ukazatel u diabetes mellitus a u rozvoje karcinomu pankreatu.
Cas Lek Cesk
; 154(3): 122-6, 2015.
Article
em Cs
| MEDLINE
| ID: mdl-26311027
ABSTRACT
Pancreatic cancer is a disease with increasing incidence and high (and nearly unchanged) lethality that is caused mainly due to its late diagnosis. Risk factors for neoplastic transformation are especially chronic pancreatitis, diabetes mellitus, but also obesity and smoking. The search for suitable early markers becomes a key element of research in this area. Such markers could be microRNAs, short single-stranded RNA molecules functioning as regulators of translation. This article serves as a review of contemporary evidence of microRNA in diabetes mellitus and pancreatic cancer.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Marcadores Genéticos
/
MicroRNAs
/
Diabetes Mellitus
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
Cs
Ano de publicação:
2015
Tipo de documento:
Article