Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.

Hilton, Hugo G; Guethlein, Lisbeth A; Goyos, Ana; Nemat-Gorgani, Neda; Bushnell, David A; Norman, Paul J; Parham, Peter

Hilton, Hugo G; Guethlein, Lisbeth A; Goyos, Ana; Nemat-Gorgani, Neda; Bushnell, David A; Norman, Paul J; Parham, Peter.

Afiliação

Hilton HG; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.
Guethlein LA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.
Goyos A; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.
Nemat-Gorgani N; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.
Bushnell DA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and.
Norman PJ; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.
Parham P; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305 peropa@stanford.edu.

J Immunol ; 195(7): 3160-70, 2015 Oct 01.

Article em En | MEDLINE | ID: mdl-26311903

Assuntos

Antígenos HLA-C/imunologia; Receptores KIR2DL1/imunologia; Receptores KIR2DL2/imunologia; Receptores KIR2DL3/imunologia; Receptores KIR/imunologia; Sequência de Aminoácidos; Sítios de Ligação/genética; Sítios de Ligação/imunologia; Linhagem Celular Tumoral; Epitopos/imunologia; Frequência do Gene; Antígenos HLA-C/genética; Haplótipos/genética; Células HeLa; Humanos; Células Matadoras Naturais/imunologia; Polimorfismo de Nucleotídeo Único; Ligação Proteica/genética; Ligação Proteica/imunologia; Estrutura Terciária de Proteína/genética; Receptores KIR/genética; Receptores KIR2DL1/genética; Receptores KIR2DL2/genética; Receptores KIR2DL3/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos HLA-C / Receptores KIR / Receptores KIR2DL1 / Receptores KIR2DL2 / Receptores KIR2DL3 Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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