Information processing in patients in vegetative and minimally conscious states.
Clin Neurophysiol
; 127(2): 1395-1402, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26315366
ABSTRACT
OBJECTIVE:
Evaluation of a short two-tone oddball paradigm to discriminate between the vegetative state (VS) and minimal consciousness state (MCS) in a sample of patients with severe disorders of consciousness (DOC).METHOD:
EEG was recorded from 45 DOC patients and 14 healthy participants while listening to an auditory oddball paradigm presented in a passive - just listen - and an active - count the odd tones - condition. In patients, the experiment was repeated after a minimum of one week.RESULTS:
Prevalence of the P300 was higher in healthy participants (71%) than in patients, but did not discriminate between VS (T1 â¼10%; T2 â¼11%) and MCS (T1 â¼13%; T2 25%) patients.CONCLUSION:
Results cast doubt on whether this simple auditory stimulation paradigm, which requires cognitive action from the listener, is sensitive enough to discriminate between patients with DOC.SIGNIFICANCE:
The sensitivity of the P300 ERP obtained in a short two-tone oddball paradigm presented in a passive and an active condition appears to be too low for routine application in a clinical setting aiming at distinguishing between VS and MCS patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estimulação Acústica
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Estado Vegetativo Persistente
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Potenciais Evocados P300
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Eletroencefalografia
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Processos Mentais
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article