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Identification and Characterization of an Irreversible Inhibitor of CDK2.
Anscombe, Elizabeth; Meschini, Elisa; Mora-Vidal, Regina; Martin, Mathew P; Staunton, David; Geitmann, Matthis; Danielson, U Helena; Stanley, Will A; Wang, Lan Z; Reuillon, Tristan; Golding, Bernard T; Cano, Celine; Newell, David R; Noble, Martin E M; Wedge, Stephen R; Endicott, Jane A; Griffin, Roger J.
Afiliação
  • Anscombe E; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Meschini E; Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
  • Mora-Vidal R; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Martin MP; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Staunton D; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Geitmann M; Beactica AB, Box 567, 751 22 Uppsala, Sweden.
  • Danielson UH; Beactica AB, Box 567, 751 22 Uppsala, Sweden; Department of Chemistry-BMC, Uppsala University, 751 23 Uppsala, Sweden.
  • Stanley WA; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Wang LZ; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Reuillon T; Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
  • Golding BT; Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK. Electronic address: bernard.golding@ncl.ac.uk.
  • Cano C; Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
  • Newell DR; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Noble ME; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Wedge SR; Newcastle Cancer Centre, Northern Institute for Cancer Research, Paul O'Gorman Building, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
  • Endicott JA; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. Electronic address: jane.endicott@ncl.ac.uk.
  • Griffin RJ; Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Chem Biol ; 22(9): 1159-64, 2015 Sep 17.
Article em En | MEDLINE | ID: mdl-26320860

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Inibidores de Proteínas Quinases / Quinase 2 Dependente de Ciclina Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Inibidores de Proteínas Quinases / Quinase 2 Dependente de Ciclina Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article