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Non-ß-blocking R-carvedilol enantiomer suppresses Ca2+ waves and stress-induced ventricular tachyarrhythmia without lowering heart rate or blood pressure.
Zhang, Jingqun; Zhou, Qiang; Smith, Chris D; Chen, Haiyan; Tan, Zhen; Chen, Biyi; Nani, Alma; Wu, Guogen; Song, Long-Sheng; Fill, Michael; Back, Thomas G; Chen, S R Wayne.
Afiliação
  • Zhang J; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Zhou Q; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Smith CD; Department of Chemistry, University of Calgary, Calgary, Alberta, Canada, T2N 1N4.
  • Chen H; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Tan Z; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Chen B; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, U.S.A.
  • Nani A; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Wu G; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A.
  • Song LS; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, U.S.A.
  • Fill M; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A. michael_fill@rush.edu tgback@ucalgary.ca swchen@ucalgary.ca.
  • Back TG; Department of Chemistry, University of Calgary, Calgary, Alberta, Canada, T2N 1N4 michael_fill@rush.edu tgback@ucalgary.ca swchen@ucalgary.ca.
  • Chen SR; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 U.S.A. The Libin Cardiovascular Institute of Alberta, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada, T2N 4N1 michael_fill@rush.edu tgback@ucalgary.ca swch
Biochem J ; 470(2): 233-42, 2015 Sep 01.
Article em En | MEDLINE | ID: mdl-26348911
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propanolaminas / Carbazóis / Cálcio / Taquicardia Ventricular / Antiarrítmicos Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propanolaminas / Carbazóis / Cálcio / Taquicardia Ventricular / Antiarrítmicos Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article