[Therapeutic approaches using genetically modified cells]. / Genetisch modifizierte Zellen zur Therapie verschiedener Erkrankungen.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
; 58(11-12): 1274-80, 2015 Nov.
Article
em De
| MEDLINE
| ID: mdl-26349563
ABSTRACT
Medicinal products containing genetically modified cells are, in most cases, classified as gene therapy and cell therapy medicinal products. Although no medicinal product containing genetically modified cells has been licensed in Europe yet, a variety of therapeutic strategies using genetically modified cells are in different stages of clinical development for the treatment of acquired and inherited diseases. In this chapter, several examples of promising approaches are presented, with an emphasis on gene therapy for inherited immunodeficiencies and on tumour immunotherapy with genetically modified T-cells expressing a chimeric antigen receptor or a recombinant T-cell receptor.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
/
Engenharia Genética
/
Terapias em Estudo
/
Terapia Baseada em Transplante de Células e Tecidos
Limite:
Humans
Idioma:
De
Ano de publicação:
2015
Tipo de documento:
Article