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[Is it possible to cure HIV infection?]. / ¿Es posible la curación de la infección VIH?
Gutiérrez, Carolina; Madrid, Nadia P; Moreno, Santiago.
Afiliação
  • Moreno S; Santiago Moreno, Servicio de Enfermedades Infecciosas. Hospital Universitario Ramón y Cajal Carretera de Colmenar, Km. 9,100 - 28034, Madrid, Spain. smguillen@salud.madrid.org.
Rev Esp Quimioter ; 28 Suppl 1: 54-6, 2015 Sep.
Article em Es | MEDLINE | ID: mdl-26365737
Antiretroviral therapy has significantly improved the life expectancy in HIV-infected people, but it cannot cure the disease by itself. Several barriers have been identified for the cure of HIV infection, including a reservoir of latently infected cells, persistent viral replication in tissues, and anatomical sanctuaries. The main strategy proposed for the cure of HIV consists on the administration of drugs that, through the reactivation of latent HIV, would eliminate the cell reservoir. Ongoing clinical trials have shown the proof of concept, but the efficacy of these drugs in decreasing the reservoir size has not been proved so far.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Terapia Antirretroviral de Alta Atividade Limite: Humans Idioma: Es Ano de publicação: 2015 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Terapia Antirretroviral de Alta Atividade Limite: Humans Idioma: Es Ano de publicação: 2015 Tipo de documento: Article