Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice.

Heulens, Nele; Korf, Hannelie; Cielen, Nele; De Smidt, Elien; Maes, Karen; Gysemans, Conny; Verbeken, Erik; Gayan-Ramirez, Ghislaine; Mathieu, Chantal; Janssens, Wim

Heulens, Nele; Korf, Hannelie; Cielen, Nele; De Smidt, Elien; Maes, Karen; Gysemans, Conny; Verbeken, Erik; Gayan-Ramirez, Ghislaine; Mathieu, Chantal; Janssens, Wim.

Afiliação

Heulens N; Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. nele.heulens@med.kuleuven.be.
Korf H; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. hannelie.korf@med.kuleuven.be.
Cielen N; Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. nele.cielen@med.kuleuven.be.
De Smidt E; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. elien.desmidt@med.kuleuven.be.
Maes K; Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. karen.maes@med.kuleuven.be.
Gysemans C; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. conny.gysemans@med.kuleuven.be.
Verbeken E; Translational Cell and Tissue Research, Department of Imaging and Pathology, Katholieke Universiteit Leuven, Minderbroederstraat 12, 3000, Leuven, Belgium. eric.verbeken@uzleuven.be.
Gayan-Ramirez G; Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. ghislaine.gayan-ramirez@med.kuleuven.be.
Mathieu C; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. chantal.mathieu@uzleuven.be.
Janssens W; Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium. wim.janssens@uzleuven.be.

Respir Res ; 16: 110, 2015 Sep 16.

Article em En | MEDLINE | ID: mdl-26376849

Assuntos

Pulmão/fisiopatologia; Doença Pulmonar Obstrutiva Crônica/etiologia; Fumaça; Fumar/efeitos adversos; Deficiência de Vitamina D/complicações; Animais; Líquido da Lavagem Broncoalveolar/química; Cálcio/sangue; Citocinas/metabolismo; Modelos Animais de Doenças; Progressão da Doença; Feminino; Mediadores da Inflamação/metabolismo; Pulmão/metabolismo; Pulmão/patologia; Ativação de Macrófagos; Macrófagos Alveolares; Masculino; Metaloproteinase 12 da Matriz/metabolismo; Camundongos Endogâmicos C57BL; Fagocitose; Pneumonia/etiologia; Pneumonia/fisiopatologia; Doença Pulmonar Obstrutiva Crônica/diagnóstico; Doença Pulmonar Obstrutiva Crônica/metabolismo; Doença Pulmonar Obstrutiva Crônica/fisiopatologia; Enfisema Pulmonar/etiologia; Enfisema Pulmonar/fisiopatologia; Explosão Respiratória; Fatores de Risco; Fatores de Tempo; Vitamina D/análogos & derivados; Vitamina D/sangue; Deficiência de Vitamina D/diagnóstico; Deficiência de Vitamina D/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumaça / Deficiência de Vitamina D / Fumar / Doença Pulmonar Obstrutiva Crônica / Pulmão Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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