Histological study of the occipital bone from patients with Chiari I malformation.
Childs Nerv Syst
; 32(2): 351-3, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26391784
ABSTRACT
BACKGROUND:
This study is focused on the histologic characteristics of occipital bone removed during Chiari I decompression in the hope of discovering unique features that may be related to the pathogenesis of this condition.METHODS:
Ten consecutive pediatric patients with Chiari I malformation underwent standard posterior fossa decompression surgery. Bone that was removed from the posterior fossa was sent for histological examination. Bone from age-matched controls also underwent histological analysis.RESULTS:
For all study and control specimens, bony samples were found to be made up of dense lamellar bone without marrow elements. In all aspects, histologically, the bone tissue had a normal appearance compared to control samples.CONCLUSIONS:
Although many authors have mentioned that the occipital bone in patients with Chiari I malformation is abnormal on imaging or at operation (e.g., thinned, thickened), based on our study, there is no histological difference between the occipital bone removed at operation and controls.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Malformação de Arnold-Chiari
/
Osso Occipital
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article