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From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors.
Al-Asri, Jamil; Fazekas, Erika; Lehoczki, Gábor; Perdih, Andrej; Görick, Cornelia; Melzig, Matthias F; Gyémánt, Gyöngyi; Wolber, Gerhard; Mortier, Jérémie.
Afiliação
  • Al-Asri J; Freie Universität Berlin, Institute of Pharmacy, Department of Pharmaceutical & Medicinal Chemistry, Königin-Luise Str. 2-4, 14195 Berlin, Germany.
  • Fazekas E; University of Debrecen, Department of Inorganic & Analytical Chemistry, Egyetem ter 1, PO Box 21, H-4032 Debrecen, Hungary.
  • Lehoczki G; University of Debrecen, Department of Inorganic & Analytical Chemistry, Egyetem ter 1, PO Box 21, H-4032 Debrecen, Hungary.
  • Perdih A; National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.
  • Görick C; Freie Universität Berlin, Institute of Pharmacy, Department of Pharmaceutical & Medicinal Chemistry, Königin-Luise Str. 2-4, 14195 Berlin, Germany.
  • Melzig MF; Freie Universität Berlin, Institute of Pharmacy, Department of Pharmaceutical & Medicinal Chemistry, Königin-Luise Str. 2-4, 14195 Berlin, Germany.
  • Gyémánt G; University of Debrecen, Department of Inorganic & Analytical Chemistry, Egyetem ter 1, PO Box 21, H-4032 Debrecen, Hungary.
  • Wolber G; Freie Universität Berlin, Institute of Pharmacy, Department of Pharmaceutical & Medicinal Chemistry, Königin-Luise Str. 2-4, 14195 Berlin, Germany. Electronic address: gerhard.wolber@fu-berlin.de.
  • Mortier J; Freie Universität Berlin, Institute of Pharmacy, Department of Pharmaceutical & Medicinal Chemistry, Königin-Luise Str. 2-4, 14195 Berlin, Germany. Electronic address: jeremie.mortier@fu-berlin.de.
Bioorg Med Chem ; 23(20): 6725-32, 2015 Oct 15.
Article em En | MEDLINE | ID: mdl-26395057
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboidratos / Inibidores Enzimáticos / Alfa-Amilases Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboidratos / Inibidores Enzimáticos / Alfa-Amilases Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article