Where does innovation adaptation end and experimentation begin?

ABSTRACT

Dr U. Nique is internationally known for contributions in vascular surgery. An elderly man, a top governmental leader in his country, is in Dr Nique's clinic for evaluation of a recurrent complex thoracoabdominal aneurysm. It was treated inadequately by a vascular surgeon in another country and was redone without success. It still poses a threat to the man's life. Because of the unusual reconstructions, a one-of-a-kind repair is needed. Dr Nique has never done such a repair and, if someone else has, they have not published their results. What considerations should apply to this case?