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What if stem cells turn into embryos in a dish?
Pera, Martin F; de Wert, Guido; Dondorp, Wybo; Lovell-Badge, Robin; Mummery, Christine L; Munsie, Megan; Tam, Patrick P.
Afiliação
  • Pera MF; Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Victoria, Australia.
  • de Wert G; The Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.
  • Dondorp W; The Florey Neuroscience and Mental Health Institute, Parkville, Victoria, Australia.
  • Lovell-Badge R; Department of Health, Ethics &Society, Research Schools Care and Public Health Research Institute and GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Mummery CL; Department of Health, Ethics &Society, Research Schools Care and Public Health Research Institute and GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Munsie M; Francis Crick Institute, Mill Hill, London, UK.
  • Tam PP; Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands.
Nat Methods ; 12(10): 917-9, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26418764
ABSTRACT
Recent studies show that pluripotent stem cells can undergo self-organized development in vitro into structures that mimic the body plan of the post-implantation embryo. Modeling human embryogenesis in a dish opens up new possibilities for the study of early development and developmental disorders, but it may also raise substantial ethical concerns.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Pesquisas com Embriões / Embrião de Mamíferos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Pesquisas com Embriões / Embrião de Mamíferos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article