Recql5 protects against lipopolysaccharide/D-galactosamine-induced liver injury in mice.

Liao, Wan-Qin; Qi, Ya-Lei; Wang, Lin; Dong, Xiao-Ming; Xu, Tao; Ding, Chao-Dong; Liu, Rui; Liang, Wei-Cheng; Lu, Li-Ting; Li, He; Li, Wen-Feng; Luo, Guang-Bin; Lu, Xin-Cheng

Liao, Wan-Qin; Qi, Ya-Lei; Wang, Lin; Dong, Xiao-Ming; Xu, Tao; Ding, Chao-Dong; Liu, Rui; Liang, Wei-Cheng; Lu, Li-Ting; Li, He; Li, Wen-Feng; Luo, Guang-Bin; Lu, Xin-Cheng.

Afiliação

Liao WQ; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Qi YL; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Wang L; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Dong XM; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Xu T; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Ding CD; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Liu R; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Liang WC; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Lu LT; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Li H; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Li WF; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Luo GB; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.
Lu XC; Wan-Qin Liao, Ya-Lei Qi, Lin Wang, Xiao-Ming Dong, Tao Xu, Chao-Dong Ding, Rui Liu, Wei-Cheng Liang, Li-Ting Lu, Xin-Cheng Lu, School of Basic Medical Science, Wenzhou Medical University, Chashan Campus, Chashan University Town, Wenzhou 325027, Zhejiang Province, China.

World J Gastroenterol ; 21(36): 10375-84, 2015 Sep 28.

Article em En | MEDLINE | ID: mdl-26420964

Assuntos

Doença Hepática Induzida por Substâncias e Drogas/prevenção & controle; Galactosamina; Hepatócitos/enzimologia; Lipopolissacarídeos; Fígado/enzimologia; RecQ Helicases/metabolismo; Animais; Apoptose; Caspase 3/metabolismo; Doença Hepática Induzida por Substâncias e Drogas/enzimologia; Doença Hepática Induzida por Substâncias e Drogas/etiologia; Doença Hepática Induzida por Substâncias e Drogas/genética; Doença Hepática Induzida por Substâncias e Drogas/patologia; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Citocinas/genética; Citocinas/metabolismo; Dano ao DNA; Modelos Animais de Doenças; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Hepatócitos/patologia; Mediadores da Inflamação/metabolismo; Fígado/patologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Infiltração de Neutrófilos; Estresse Oxidativo; Fosforilação; RecQ Helicases/deficiência; RecQ Helicases/genética; Transdução de Sinais/efeitos dos fármacos; Fatores de Tempo

Palavras-chave

Apoptosis; CYP450; Liver injury; Oxidative stress; Recql5

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Hepatócitos / RecQ Helicases / Doença Hepática Induzida por Substâncias e Drogas / Galactosamina / Fígado Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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