Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD.

Wielscher, Matthias; Vierlinger, Klemens; Kegler, Ulrike; Ziesche, Rolf; Gsur, Andrea; Weinhäusel, Andreas

Wielscher, Matthias; Vierlinger, Klemens; Kegler, Ulrike; Ziesche, Rolf; Gsur, Andrea; Weinhäusel, Andreas.

Afiliação

Wielscher M; AIT - Austrian Institute of Technology, Health & Environment Department, Molecular Diagnostics Unit, Muthgasse 11/2, 1190 Vienna, Austria.
Vierlinger K; AIT - Austrian Institute of Technology, Health & Environment Department, Molecular Diagnostics Unit, Muthgasse 11/2, 1190 Vienna, Austria.
Kegler U; AIT - Austrian Institute of Technology, Health & Environment Department, Molecular Diagnostics Unit, Muthgasse 11/2, 1190 Vienna, Austria.
Ziesche R; Medical University of Vienna, Clinical Department for Pulmonology, Spitalgasse 23, 1090 Vienna, Austria.
Gsur A; Medical University of Vienna, Institute of Cancer Research, Borschkegasse 8A, 1090 Vienna, Austria.
Weinhäusel A; AIT - Austrian Institute of Technology, Health & Environment Department, Molecular Diagnostics Unit, Muthgasse 11/2, 1190 Vienna, Austria.

EBioMedicine ; 2(8): 929-36, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26425700

Assuntos

Metilação de DNA; DNA de Neoplasias/sangue; Neoplasias Pulmonares/sangue; Doença Pulmonar Obstrutiva Crônica/sangue; Fibrose Pulmonar/sangue; Idoso; DNA de Neoplasias/genética; Feminino; Humanos; Neoplasias Pulmonares/genética; Masculino; Pessoa de Meia-Idade; Doença Pulmonar Obstrutiva Crônica/genética; Fibrose Pulmonar/genética

Palavras-chave

AUC, area under curve; Biomarker; COPD, chronic obstructive pulmonary disease; Ct-value, cycle threshold; HOXD10; HP, hypersensitivity pneumonitis; ILD, interstitial lung disease, IPF, idiopathic pulmonary fibrosis; Liquid biopsy; MSP, methyl specific priming; MSRE, methyl sensitive restriction enzyme; NSIP, non-specific interstitial pneumonitis; PAX9; ROC, receiver operating characteristics; UIP, usual interstitial pneumonia; cfDNA, cell-free DNA; methyl-sensitive restriction enzyme; multiplex PCR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / DNA de Neoplasias / Metilação de DNA / Doença Pulmonar Obstrutiva Crônica / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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