The Utility of Positron Emission Tomography in Epilepsy.
Can J Neurol Sci
; 42(6): 360-71, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26437611
ABSTRACT
The role of fludeoxyglucose F 18 positron emission tomography (PET) in the presurgical evaluation of patients with medically intractable epilepsy continues to be refined. The purpose of this study was to systematically review the literature to assess the diagnostic accuracy and utility of PET in this setting. Thirty-nine studies were identified through MEDLINE and EMBASE databases that met the inclusion criteria. In adult patients, PET hypometabolism showed a 56 to 90% agreement with seizure onset localized by intracranial electroencephalogram (pediatric 21 to 86%). In temporal lobe epilepsy patients with good surgical outcome, PET displayed moderate to high sensitivity in localizing the seizure focus (range 71 to 89%). The sensitivity increased by 8 to 23% when PET results were combined with magnetic resonance imaging or electroencephalogram. PET has been shown to affect patient management by improving the guidance of intracranial electrodes placement, altering the decision to perform surgery, or excluding patients from further evaluation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Resultado do Tratamento
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Fluordesoxiglucose F18
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Tomografia por Emissão de Pósitrons
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Eletroencefalografia
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Epilepsia
Tipo de estudo:
Diagnostic_studies
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Guideline
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Prognostic_studies
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Systematic_reviews
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article