Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase.
FEBS Lett
; 589(21): 3321-7, 2015 Oct 24.
Article
em En
| MEDLINE
| ID: mdl-26452715
ABSTRACT
Yak1 is a member of dual-specificity Tyr phosphorylation-regulated kinases (DYRKs) that are evolutionarily conserved. The downstream targets of Yak1 and their functions are largely unknown. Here, a homologous protein AtYAK1 was identified in Arabidopsis thaliana and the phosphoprotein profiles of the wild type and an atyak1 mutant were compared on two-dimensional gel following Pro-Q Diamond phosphoprotein gel staining. Annexin1, Annexin2 and RBD were phosphorylated at serine/threonine residues by the AtYak1 kinase. Annexin1, Annexin2 and Annexin4 were also phosphorylated at tyrosine residues. Our study demonstrated that AtYak1 is a dual specificity protein kinase in Arabidopsis that may regulate the phosphorylation status of the annexin family proteins.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfoproteínas
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Proteínas Serina-Treonina Quinases
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Arabidopsis
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Proteínas de Arabidopsis
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article