Polymeric oncolytic adenovirus for cancer gene therapy.

Choi, Joung-Woo; Lee, Young Sook; Yun, Chae-Ok; Kim, Sung Wan

Choi, Joung-Woo; Lee, Young Sook; Yun, Chae-Ok; Kim, Sung Wan.

Afiliação

Choi JW; Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, USA.
Lee YS; Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, USA.
Yun CO; Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea. Electronic address: chaeok@hanyang.ac.kr.
Kim SW; Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, USA.

J Control Release ; 219: 181-191, 2015 Dec 10.

Article em En | MEDLINE | ID: mdl-26453806

Assuntos

Adenoviridae; Terapia Genética; Neoplasias/terapia; Vírus Oncolíticos; Polímeros; Adenoviridae/química; Animais; Vetores Genéticos; Humanos; Terapia Viral Oncolítica/métodos; Vírus Oncolíticos/química; Polímeros/química; Eletricidade Estática; Microambiente Tumoral

Palavras-chave

Active targeting; Cancer gene therapy; Clinical trials; Oncolytic Ad/polymer hybrid vector; Oncolytic adenovirus; Systemic administration; Tumor microenvironment targeting

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Terapia Genética / Adenoviridae / Vírus Oncolíticos / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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