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Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Paternoster, Lavinia; Standl, Marie; Waage, Johannes; Baurecht, Hansjörg; Hotze, Melanie; Strachan, David P; Curtin, John A; Bønnelykke, Klaus; Tian, Chao; Takahashi, Atsushi; Esparza-Gordillo, Jorge; Alves, Alexessander Couto; Thyssen, Jacob P; den Dekker, Herman T; Ferreira, Manuel A; Altmaier, Elisabeth; Sleiman, Patrick Ma; Xiao, Feng Li; Gonzalez, Juan R; Marenholz, Ingo; Kalb, Birgit; Yanes, Maria Pino; Xu, Cheng-Jian; Carstensen, Lisbeth; Groen-Blokhuis, Maria M; Venturini, Cristina; Pennell, Craig E; Barton, Sheila J; Levin, Albert M; Curjuric, Ivan; Bustamante, Mariona; Kreiner-Møller, Eskil; Lockett, Gabrielle A; Bacelis, Jonas; Bunyavanich, Supinda; Myers, Rachel A; Matanovic, Anja; Kumar, Ashish; Tung, Joyce Y; Hirota, Tomomitsu; Kubo, Michiaki; McArdle, Wendy L; Henderson, A J; Kemp, John P; Zheng, Jie; Smith, George Davey; Rüschendorf, Franz; Bauerfeind, Anja; Lee-Kirsch, Min Ae; Arnold, Andreas.
Afiliação
  • Paternoster L; Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Standl M; School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • Waage J; Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
  • Baurecht H; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Hotze M; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Strachan DP; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Curtin JA; Population Health Research Institute, St George's, University of London, London, UK.
  • Bønnelykke K; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
  • Tian C; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Takahashi A; 23andMe, Inc., Mountain View, CA, USA.
  • Esparza-Gordillo J; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Yokohama, Japan.
  • Alves AC; Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin, Germany.
  • Thyssen JP; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • den Dekker HT; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
  • Ferreira MA; National Allergy Research Centre, Department of Dermatology and Allergology, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Altmaier E; Department of Pediatrics, Erasmus MC, Rotterdam, the Netherlands.
  • Sleiman PM; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
  • Xiao FL; The Generation R Study Group, Erasmus MC, Rotterdam, the Netherlands.
  • Gonzalez JR; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Marenholz I; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Kalb B; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
  • Yanes MP; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Xu CJ; The Center for Applied Genomics, The Children's Hospital of Philadelphia, PA, USA.
  • Carstensen L; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Groen-Blokhuis MM; Institute of Dermatology, Anhui Medical University, Hefei, Anhui, China.
  • Venturini C; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
  • Pennell CE; Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin, Germany.
  • Barton SJ; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Levin AM; Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin, Germany.
  • Curjuric I; Pediatric Pneumology and Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Bustamante M; Department of Medicine, University of California, San Francisco, CA, USA.
  • Kreiner-Møller E; Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
  • Lockett GA; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.
  • Bacelis J; University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.
  • Bunyavanich S; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.
  • Myers RA; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Matanovic A; Dept Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, the Netherlands.
  • Kumar A; KCL Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Tung JY; School of Women's and Infants' Health, The University of Western Australia (UWA), Perth, Australia.
  • Hirota T; Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
  • Kubo M; Department of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
  • McArdle WL; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Henderson AJ; University of Basel, Basel, Switzerland.
  • Kemp JP; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
  • Zheng J; Centre for Genomic Regulation (CRG), Barcelona, Spain.
  • Smith GD; Pompeu Fabra University (UPF), Barcelona, Spain.
  • Rüschendorf F; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
  • Bauerfeind A; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Lee-Kirsch MA; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Arnold A; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Sahlgrenska University Hosptial, Gothenburg, Sweden.
Nat Genet ; 47(12): 1449-1456, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26482879

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Etnicidade / Marcadores Genéticos / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Dermatite Atópica / Estudo de Associação Genômica Ampla / Loci Gênicos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Etnicidade / Marcadores Genéticos / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Dermatite Atópica / Estudo de Associação Genômica Ampla / Loci Gênicos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article