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Functionalized nanomaterials: are they effective to perform gene delivery to difficult-to-transfect cells with no cytotoxicity?
Tonelli, F M P; Lacerda, S M S N; Paiva, N C O; Pacheco, F G; Scalzo Junior, S R A; de Macedo, F H P; Cruz, J S; Pinto, M C X; Corrêa Junior, J D; Ladeira, L O; França, L R; Guatimosim, S; Resende, R R.
Afiliação
  • Tonelli FM; Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
  • Lacerda SM; Cell Biology Laboratory, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Paiva NC; Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
  • Pacheco FG; Chemistry of Nanostructures Laboratory, Nuclear Technology Development Center, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Scalzo Junior SR; Cell Electrophysiology Laboratory, Department of Physiology and Pharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • de Macedo FH; Excitable Membranes Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Cruz JS; Excitable Membranes Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Pinto MC; Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
  • Corrêa Junior JD; Laboratory of Chemical-Biological Interactions and Animal Reproduction, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Ladeira LO; Nanomaterials Laboratory, Department of Physics, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • França LR; Cell Biology Laboratory, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Guatimosim S; Cell Electrophysiology Laboratory, Department of Physiology and Pharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Resende RR; Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
Nanoscale ; 7(43): 18036-43, 2015 Nov 21.
Article em En | MEDLINE | ID: mdl-26486874
ABSTRACT
Nanodiamonds (NDs), multiwalled carbon nanotubes (MWCNTs) and gold nanorods (NRs) can be functionalized to promote gene delivery to hard-to-transfect cells with higher transfection efficiency than cationic lipids, and inducing less cell death.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transfecção / Nanoestruturas Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transfecção / Nanoestruturas Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article