Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation.

Dhanesha, Nirav; Ahmad, Ajmal; Prakash, Prem; Doddapattar, Prakash; Lentz, Steven R; Chauhan, Anil K

Dhanesha, Nirav; Ahmad, Ajmal; Prakash, Prem; Doddapattar, Prakash; Lentz, Steven R; Chauhan, Anil K.

Afiliação

Dhanesha N; From the Department of Internal Medicine, University of Iowa, Iowa City.
Ahmad A; From the Department of Internal Medicine, University of Iowa, Iowa City.
Prakash P; From the Department of Internal Medicine, University of Iowa, Iowa City.
Doddapattar P; From the Department of Internal Medicine, University of Iowa, Iowa City.
Lentz SR; From the Department of Internal Medicine, University of Iowa, Iowa City.
Chauhan AK; From the Department of Internal Medicine, University of Iowa, Iowa City. anil-chauhan@uiowa.edu.

Circulation ; 132(23): 2237-47, 2015 Dec 08.

Article em En | MEDLINE | ID: mdl-26508731

Assuntos

Modelos Animais de Doenças; Fibronectinas/genética; Deleção de Genes; Hipercolesterolemia/genética; Acidente Vascular Cerebral/genética; Animais; Feminino; Fibronectinas/deficiência; Hipercolesterolemia/patologia; Hipercolesterolemia/terapia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Acidente Vascular Cerebral/patologia; Acidente Vascular Cerebral/prevenção & controle; Resultado do Tratamento

Palavras-chave

fibronectins; hypercholesterolemia; inflammation; stroke; thrombosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibronectinas / Deleção de Genes / Acidente Vascular Cerebral / Modelos Animais de Doenças / Hipercolesterolemia Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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