Your browser doesn't support javascript.
loading
Nonconventional three-finger toxin BMLCL from krait Bungarus multicinctus venom with high affinity interacts with nicotinic acetylcholine receptors.
Utkin, Yu N; Kasheverov, I E; Kudryavtsev, D S; Andreeva, T V; Starkov, V G; Ziganshin, R H; Kuznetsov, D V; Anh, Hoang Ngoc; Thao, Nguyen Thi Thanh; Khoa, Nguyen Cuu; Tsetlin, V I.
Afiliação
  • Utkin YN; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia. utkin@mx.ibch.ru.
  • Kasheverov IE; The National University of Science and Technology MISiS, Moscow, Russia. utkin@mx.ibch.ru.
  • Kudryavtsev DS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
  • Andreeva TV; Syneuro Ltd., Moscow, Russia.
  • Starkov VG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
  • Ziganshin RH; Syneuro Ltd., Moscow, Russia.
  • Kuznetsov DV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
  • Anh HN; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
  • Thao NT; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
  • Khoa NC; The National University of Science and Technology MISiS, Moscow, Russia.
  • Tsetlin VI; Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Dokl Biochem Biophys ; 464: 294-7, 2015.
Article em En | MEDLINE | ID: mdl-26518551
ABSTRACT
Nonconventional three-finger toxin BMLCL was isolated from B. multicinctus venom, and its interaction with different subtypes of nicotinic acetylcholine receptor (nAChR) was studied. It was found that BMLCL is able to interact with high efficiency with both α7 and muscle type nAChRs.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bungarotoxinas / Receptores Nicotínicos / Colinérgicos / Proteínas de Répteis Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bungarotoxinas / Receptores Nicotínicos / Colinérgicos / Proteínas de Répteis Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article