Down-regulation of ribosomal protein S15A inhibits proliferation of human glioblastoma cells in vivo and in vitro via AKT pathway.

Yao, Yiqun; Liu, Yongjian; Lv, Xiupeng; Dong, Bin; Wang, Feng; Li, Jun; Zhang, Qiuping; Xu, Ruixue; Xu, Yinghui

Yao, Yiqun; Liu, Yongjian; Lv, Xiupeng; Dong, Bin; Wang, Feng; Li, Jun; Zhang, Qiuping; Xu, Ruixue; Xu, Yinghui.

Afiliação

Yao Y; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China.
Liu Y; Department of interventional therapy, First Affiliated Hospital, Dalian Medical University, Dalian, People's Republic of China.
Lv X; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China.
Dong B; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China.
Wang F; Department of interventional therapy, First Affiliated Hospital, Dalian Medical University, Dalian, People's Republic of China.
Li J; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China.
Zhang Q; Department of Pathology, First Affiliated Hospital, Dalian Medical University, Dalian, People's Republic of China.
Xu R; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China.
Xu Y; Department of Neurosurgery, First Affiliated Hospital, Dalian Medical University, 222 Zhong Shan Road, Dalian, 116011, People's Republic of China. doctorliuyj@163.com.

Tumour Biol ; 37(4): 4979-90, 2016 Apr.

Article em En | MEDLINE | ID: mdl-26537582

Assuntos

Proliferação de Células/genética; Glioblastoma/genética; Proteína Oncogênica v-akt/genética; Proteínas Ribossômicas/biossíntese; Adulto; Idoso; Animais; Ciclo Celular/genética; Linhagem Celular Tumoral; Feminino; Regulação Neoplásica da Expressão Gênica; Glioblastoma/patologia; Humanos; Lentivirus/genética; Masculino; Camundongos; Pessoa de Meia-Idade; Interferência de RNA; RNA Mensageiro/biossíntese; Proteínas Ribossômicas/genética; Transdução de Sinais; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

AKT pathway; Glioblastoma; Glioma; RPS15A; Therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / Glioblastoma / Proliferação de Células / Proteína Oncogênica v-akt Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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