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A novel aptasensor for thrombin detection based on alkaline phosphatase decorated ZnO/Pt nanoflowers as signal amplifiers.
Lv, J J; Yang, Z H; Zhuo, Y; Yuan, R; Chai, Y Q.
Afiliação
  • Lv JJ; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
  • Yang ZH; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
  • Zhuo Y; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
  • Yuan R; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
  • Chai YQ; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
Analyst ; 140(24): 8088-91, 2015 Dec 21.
Article em En | MEDLINE | ID: mdl-26548406
To remedy the problems caused by the introduction of an additional electron mediator and realize signal amplification, a new strategy has been presented to construct an electrochemical aptasensor for thrombin detection based on the cascade electrocatalysis of alkaline phosphatase (ALP) and Pt nanoparticle (PtNP)-functionalized ZnO nanoflowers.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óxido de Zinco / Trombina / Técnicas de Química Analítica / Fosfatase Alcalina / Aptâmeros de Nucleotídeos / Nanopartículas Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óxido de Zinco / Trombina / Técnicas de Química Analítica / Fosfatase Alcalina / Aptâmeros de Nucleotídeos / Nanopartículas Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article