Preliminary Investigation of Cerebral Blood Flow and Amyloid Burden in Veterans With and Without Combat-Related Traumatic Brain Injury.
J Neuropsychiatry Clin Neurosci
; 28(2): 89-96, 2016.
Article
em En
| MEDLINE
| ID: mdl-26548655
ABSTRACT
This study aimed to examine global and regional cerebral blood flow and amyloid burden in combat veterans with and without traumatic brain injury (TBI). Cerebral blood flow (in milliliters per minute per 100 mL) was measured by quantitative [(15)O]water, and amyloid burden was measured by [(11)C]PIB imaging. Mean global cerebral blood flow was significantly lower in veterans with TBI compared with non-TBI veterans. There were essentially no differences between groups for globally normalized regional cerebral blood flow. Amyloid burden did not differ between TBI and non-TBI veterans. Veterans who have suffered a TBI have significantly lower cerebral blood flow than non-TBI controls but did not manifest increased levels of amyloid, globally or regionally.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Veteranos
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Encéfalo
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Circulação Cerebrovascular
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Lesões Encefálicas Traumáticas
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Amiloide
Limite:
Adult
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Humans
/
Male
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article