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Transcription factor Ets-1 links glucotoxicity to pancreatic beta cell dysfunction through inhibiting PDX-1 expression in rodent models.
Chen, Fang; Sha, Min; Wang, Yanyang; Wu, Tijun; Shan, Wei; Liu, Jia; Zhou, Wenbo; Zhu, Yunxia; Sun, Yujie; Shi, Yuguang; Bleich, David; Han, Xiao.
Afiliação
  • Chen F; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Sha M; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Wang Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Wu T; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Shan W; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Liu J; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Zhou W; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Zhu Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Sun Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
  • Shi Y; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX, USA.
  • Bleich D; Rutgers New Jersey Medical School, Newark, NJ, USA.
  • Han X; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China. hanxiao@njmu.edu.cn.
Diabetologia ; 59(2): 316-24, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26564177
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Proteínas de Homeodomínio / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Proteína Proto-Oncogênica c-ets-1 / Hiperglicemia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Proteínas de Homeodomínio / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Proteína Proto-Oncogênica c-ets-1 / Hiperglicemia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article