Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids.

Zignego, Donald L; Hilmer, Jonathan K; June, Ronald K

Zignego, Donald L; Hilmer, Jonathan K; June, Ronald K.

Afiliação

Zignego DL; Department of Mechanical and Industrial Engineering, Montana State University, United States.
Hilmer JK; Department of Chemistry and Biochemistry, Montana State University, United States.
June RK; Department of Mechanical and Industrial Engineering, Montana State University, United States; Department of Cell Biology and Neurosciences, Montana State University, United States; Department of Orthopaedics and Sports Medicine, University of Washington, United States. Electronic address: rjune@me.montana.edu.

J Biomech ; 48(16): 4253-61, 2015 Dec 16.

Article em En | MEDLINE | ID: mdl-26573901

Assuntos

Condrócitos/fisiologia; Mecanotransdução Celular; Idoso; Idoso de 80 Anos ou mais; Aminoácidos/metabolismo; Cartilagem Articular/metabolismo; Células Cultivadas; Metabolismo Energético; Humanos; Metabolismo dos Lipídeos; Pessoa de Meia-Idade; Osteoartrite do Quadril/metabolismo; Osteoartrite do Quadril/patologia

Palavras-chave

Chondrocyte biology; Mechanotransduction; Metabolomics; Osteoarthritis; Systems biology

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Condrócitos / Mecanotransdução Celular Limite: Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google