Practical guide to sample size calculations: non-inferiority and equivalence trials.
Pharm Stat
; 15(1): 80-9, 2016.
Article
em En
| MEDLINE
| ID: mdl-26604186
ABSTRACT
A sample size justification is a vital part of any trial design. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the steps for conducting sample size calculations for non-inferiority and equivalence trials are summarised. Practical advice and examples are provided that illustrate how to carry out the calculations by hand and using the app SampSize.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Equivalência Terapêutica
/
Ensaios Clínicos como Assunto
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Tamanho da Amostra
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article