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Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells.
Oliveira, L M A; Falomir-Lockhart, L J; Botelho, M G; Lin, K-H; Wales, P; Koch, J C; Gerhardt, E; Taschenberger, H; Outeiro, T F; Lingor, P; Schüle, B; Arndt-Jovin, D J; Jovin, T M.
Afiliação
  • Oliveira LM; Laboratory of Cellular Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
  • Falomir-Lockhart LJ; Laboratory of Cellular Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
  • Botelho MG; Laboratory of Cellular Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
  • Lin KH; Group of Membrane Biophysics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
  • Wales P; Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Waldweg 33, Göttingen, Germany.
  • Koch JC; Department of Neurology, University Medical Center Göttingen, Robert-Koch-Str. 40, Göttingen, Germany.
  • Gerhardt E; Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Waldweg 33, Göttingen, Germany.
  • Taschenberger H; Group of Membrane Biophysics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
  • Outeiro TF; DFG-Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany.
  • Lingor P; Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Waldweg 33, Göttingen, Germany.
  • Schüle B; DFG-Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany.
  • Arndt-Jovin DJ; Department of Neurology, University Medical Center Göttingen, Robert-Koch-Str. 40, Göttingen, Germany.
  • Jovin TM; DFG-Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany.
Cell Death Dis ; 6: e1994, 2015 Nov 26.
Article em En | MEDLINE | ID: mdl-26610207
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article