Systemic Gene Therapy for Targeting the CNS.
Methods Mol Biol
; 1382: 231-7, 2016.
Article
em En
| MEDLINE
| ID: mdl-26611590
ABSTRACT
Systemic gene delivery is useful for modeling and treatment of a body-wide disease. Recently, it has been shown that certain agents, when delivered systemically, can efficiently target the central nervous system. This technique has been used to model and treat rodent models of neurological disease with unprecedented success. Here, we describe intravenous delivery in neonate and adult mice. These techniques are easily learned and have minimal equipment requirements.
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Texto completo:
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
/
Sistema Nervoso Central
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Dependovirus
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Doenças do Sistema Nervoso
Limite:
Animals
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article